abstract：:As Guinea worm eradication programmes have got under way in endemic countries over the last decade, there has been a shift towards more participatory methods. The approach to surveillance has changed from periodic cross-sectional surveys to monthly village-based reporting of cases by a volunteer village health worker....

journal_title：Acta tropica

authors： Cairncross S,Braide EI,Bugri SZ

更新日期：1996-04-01 00:00:00

abstract：:Mefloquine base, (12.5 mg/kg body weight), was administered as a single oral dose to 34 pregnant women with Plasmodium falciparum parasitaemia. They were followed up in vivo using the modified 28-day WHO extended field test. The sensitivity of P. falciparum isolates obtained from these women to mefloquine (MQ) was eva...

journal_title：Acta tropica

authors： Okoyeh JN,Lege-Oguntoye L,Emembolu JO,Sarki U

更新日期：1996-03-01 00:00:00

abstract：:Six Cercopithecus aethiops monkeys, 4 Theropithecus gelada baboons and 2 Papio anubis baboons were infected using Leishmania aethiopica isolates originating either from localized (LCL) or diffuse (DCL) cutaneous leishmaniasis patients. The history of lesions in 4 C. aethiops monkeys infected by LCL strains mimicked th...

journal_title：Acta tropica

authors： Hailu A,Negesse Y,Abraham I

更新日期：1995-06-01 00:00:00

abstract：:Trypanosomes were isolated from the midguts of Glossina palpalis palpalis, G. pallicera pallicera and G. nigrofusca nigrofusca captured around the village of Guediboua, South West of Daloa in Côte d'Ivoire. Seventy of the 124 isolates, obtained from 688 flies, were examined for four different kinds of trypanosome usin...

journal_title：Acta tropica

authors： McNamara JJ,Laveissière C,Masiga DK

更新日期：1995-05-01 00:00:00

abstract：:As part of establishing effective methods for malaria control, the malaria-associated nutritional status was surveyed on Guadalcanal Island in the Solomon Islands in 1993. A total of 506 residents participated in this study. The slide positive rate for malaria was 54% (275/506) in all ages, with a high of 79% for chil...

journal_title：Acta tropica

authors： Mizushima Y,Kato H,Ohmae H,Tanaka T,Bobogare A,Ishii A

更新日期：1994-12-01 00:00:00

abstract：:> Qualitative research methods were used in rural and urban areas of the Greater Accra Region to generate data to describe the folk diagnosis, etiology and management of malaria. Respondents defined as fever a set of symptoms loosely concordant with clinical malaria. Primary cause of fever as heat and particularly in ...

journal_title：Acta tropica

authors： Agyepong IA,Manderson L

更新日期：1994-12-01 00:00:00

abstract：:Time to death from starvation and compulsive killing without eating of the prey by larvae of Toxorhynchites splendens were studied in the laboratory. The first and second instars survived without food for 3 days while third and fourth instars survived for 7.8 and 14 days, respectively. When the corresponding instars o...

journal_title：Acta tropica

authors： Amalraj DD,Das PK

更新日期：1994-11-01 00:00:00

abstract：:In vitro cultured Plasmodium falciparum gametocytes were fed to Anopheles gambiae (G3) mosquitoes to identify parasite population characteristics useful for predicting successful mosquito infections. Parameters were collected from an initial study of 90 infections over a two year period and a second study of 55 infect...

journal_title：Acta tropica

authors： Noden BH,Beadle PS,Vaughan JA,Pumpuni CB,Kent MD,Beier JC

更新日期：1994-10-01 00:00:00

abstract：:The paper summarizes the evolution of a biomedical field research station in Tanzania, established by a European institute, into a national health research and resource centre. The Swiss Tropical Institute Field Laboratory was founded in Ifakara in the Kilombero District in southeastern Tanzania in 1957. It has evolve...

journal_title：Acta tropica

authors： Tanner M,Kitua A,Degrémont AA

更新日期：1994-08-01 00:00:00

abstract：:This study extends the previous knowledge of the action of bacitracin zinc against xenic cultures of Entamoeba histolytica. Results presented here, using axenic E. histolytica, confirm the enhanced activity of bacitracin zinc as compared to native bacitracin and demonstrate that this enhancement is due to a direct eff...

journal_title：Acta tropica

authors： Andrews BJ

更新日期：1994-06-01 00:00:00

abstract：:The kinetic and dynamic disposition of endo- and ectoparasiticides in livestock in relation to development of resistance is examined. Based on the modes of action of antiparasitic drugs, maximum activity necessitates that the parasite be exposed to 'toxic' concentrations for as great a duration as possible. In contras...

journal_title：Acta tropica

authors： Hennessy DR

更新日期：1994-03-01 00:00:00

abstract：:Evidence for the phenomenon of multiple drug resistance (MDR) in the well studied pathogenic protozoa has been examined. This has been placed in the more familiar context of the MDR efflux transporters and the cloned mdr genes of mammalian cells. Homologues of the mdr gene family in protozoa and their possible role in...

journal_title：Acta tropica

authors： Upcroft P

更新日期：1994-03-01 00:00:00

abstract：:The risk of infection (RI) with Wuchereria bancrofti by vector mosquitoes has been conventionally estimated from the biting population of all age classes. This estimate of RI had no correlation with microfilaria (mf) prevalence and intensity of infection in humans. A new method for estimating RI from a resting populat...

journal_title：Acta tropica

authors： Vanamail P,Ramaiah KD,Das PK

更新日期：1993-12-01 00:00:00

abstract：:A monomorphic strain of Trypanosoma brucei brucei (EATRO 110) was cultured as long slender bloodstream forms in vitro for 24 h with 100 microM Eflornithine HCl. This resulted in depletion of intracellular putrescine, a greater than 50% decrease in spermidine, and a cessation of cell division. These Eflornithine treate...

journal_title：Acta tropica

authors： Giffin BF,McCann PP

更新日期：1993-11-01 00:00:00

abstract：:Indirect erythrocyte membrane immunofluorescence (EMIF), a standard method for detection of antibodies to the P. falciparum blood stage vaccine candidate antigen Pf155/RESA, has been adapted to light microscopy by enzyme-linked immunostaining of the erythrocyte membrane, using alkaline phosphatase and chromogenic subs...

journal_title：Acta tropica

authors： Udomsangpetch R,Kulane A,Berzins K,Perlmann H,Perlmann P,Flyg BW

更新日期：1993-10-01 00:00:00

abstract：:This review outlines the metabolism of polyamines in African trypanosomes and summarizes evidence to indicate that trypanosome polyamine metabolism differs in several important aspects from that of the mammalian host. These differences relate to the halflife, turnover, substrate specificity and regulation of enzymes w...

journal_title：Acta tropica

authors： Bacchi CJ,Yarlett N

更新日期：1993-09-01 00:00:00

abstract：:The prevalence of schistosomiasis due to S. japonicum is focally high in the lake regions of China, and reinfection after treatment with praziquantel is frequent. In this study, the total reinfection rate among 740 treated persons was 12.9%. Factors associated with reinfection were age and sex, water contact and the d...

journal_title：Acta tropica

authors： Wu Z,Bu K,Yuan L,Yang G,Zhu J,Liu Q

更新日期：1993-08-01 00:00:00

abstract：:The surface coat of the protozoan parasite Leishmania affords remarkable protection in the harsh environments encountered within the insect vectors and vertebrate hosts. It also provides specificity for the interaction of these parasites with the cells in the sandfly gut and with the human macrophage. Surprisingly few...

journal_title：Acta tropica

authors： Moody SF

更新日期：1993-05-01 00:00:00

abstract：:In July 1989, blood samples were collected from parasitaemic cattle in the Ghibe valley, Ethiopia, frozen in liquid nitrogen and transported to Nairobi, Kenya. Twelve of the stabilates were inoculated into individual Boran (Bos indicus) calves and characterised for their sensitivity, in turn, to diminazene aceturate (...

journal_title：Acta tropica

authors： Codjia V,Mulatu W,Majiwa PA,Leak SG,Rowlands GJ,Authié E,d'Ieteren GD,Peregrine AS

更新日期：1993-04-01 00:00:00

abstract：:Leishmania donovani promastigote glycoconjugate ligands, studied in our laboratory, that interact with the internalization receptors on BALB/c macrophages: the 'fucose mannose ligand' (FML), the 'phosphate mannogalactan ligand' (PMGL), and the 'lipopeptidephosphoglycan' (LPPD), interfered also with interaction between...

journal_title：Acta tropica

authors： Palatnik-de-Sousa CB,Dutra HS,Borojevic R

更新日期：1993-03-01 00:00:00

abstract：:The effect of vaccines against the pre-erythrocytic, the erythrocytic and the sexual stages of malaria on the transmission of malaria was examined using a simulation model of seasonal or epidemic transmission. The primary outcome of the model was the number of cases of malaria present at the end of the transmission se...

journal_title：Acta tropica

authors： Saul A

更新日期：1993-01-01 00:00:00

abstract：:A randomized controlled trial was carried out in Assab under the auspices of the National Organization for the Control of Malaria and other Vectorborne Diseases of Ethiopia to assess the effectiveness of an indigenous cyprinodontid fish, Aphanius dispar, in controlling mosquito larvae, including the local malaria vect...

journal_title：Acta tropica

authors： Fletcher M,Teklehaimanot A,Yemane G

更新日期：1992-12-01 00:00:00

abstract：:We have sequenced single kinetoplast DNA minicircles from three species and part of a minicircle from the fourth major species within the Leishmania braziliensis complex. Alignment of these sequences with each other and with those of other kinetoplastids allowed the selection of a pair of oligonucleotides suitable as ...

journal_title：Acta tropica

authors： de Bruijn MH,Barker DC

更新日期：1992-09-01 00:00:00

abstract：:Preliminary data from an ongoing epidemiological survey in the pastoral zone of Samorogouan (Kénédougou) indicate the occurrence of multiple-drug-resistant Trypanosoma congolense. Despite frequent trypanocidal drug treatments with diminazene aceturate (Berenil, Hoechst) at 7 mg/kg body weight (bw) at intervals of 2 to...

journal_title：Acta tropica

authors： Clausen PH,Sidibe I,Kaboré I,Bauer B

更新日期：1992-08-01 00:00:00

abstract：:Antibodies to the variable antigen type (VAT) designated LiTat 1.3 are common in sera from parasitologically confirmed patients with gambian sleeping sickness. For this reason, LiTat 1.3 has been considered a suitable antigen for detecting Trypanosoma brucei gambiense in the Card Agglutination Test for Trypanosomiasis...

journal_title：Acta tropica

authors： Dukes P,Gibson WC,Gashumba JK,Hudson KM,Bromidge TJ,Kaukus A,Asonganyi T,Magnus E

更新日期：1992-06-01 00:00:00

abstract：:A survey involving 77 individuals living in two savannah villages near Bobo Dioulasso (Burkina Faso, West Africa), was performed in June 1987 (before), August-September (during) and January 1988 after the seasonal transmission. The clinical longitudinal study during the seasonal period permitted us to define three dif...

journal_title：Acta tropica

authors： Chumpitazi BF,Peyron F,Boudin C,Picot S,Oury B,Ambroise-Thomas P

更新日期：1992-04-01 00:00:00

abstract：:Litomosoides carinii microfilariae were exsheathed by freezing and thawing, and the sheaths were separated by filtration. Samples of pure sheaths thus obtained were hydrolyzed, methanolyzed or oxidized with nitric acid under pressure at 300 degrees C, respectively, and were analyzed for amino acids, sugars, fatty acid...

journal_title：Acta tropica

authors： Bardehle G,Jepp-Libutzki A,Linder D,Moehnle K,Schott HH,Zahner H,Zähringer U,Stirm S

更新日期：1992-02-01 00:00:00

abstract：:We have demonstrated here that while many amastigotes of both Leishmania mexicana amazonensis and Leishmania mexicana mexicana differentiate to promastigotes when placed in culture at 27 degrees C, many others remain as amastigotes in their proliferative cycle. We have used this system to examine the effects of the an...

journal_title：Acta tropica

authors： Taylor DR,Williams GT

更新日期：1991-12-01 00:00:00

abstract：:Antigen-detection enzyme immunoassays (ELISA) were used for the diagnosis of Trypanosoma vivax, T. congolense and T. brucei in N'Dama cattle in Gabon, Central Africa. The assays are based on monoclonal antibodies which recognise trypanosome antigens specific for each of the three species and animals were termed 'antig...

journal_title：Acta tropica

authors： Trail JC,d'Ieteren GD,Maille JC,Yangari G,Nantulya VM

更新日期：1991-11-01 00:00:00

abstract：:The many mathematical models of the transmission dynamics of schistosomes that have been published since 1965 have had little impact on field studies or on the design of schistosome control programmes. At least in part, this is due to limited interaction between theoretician and field worker, resulting in unrealistic ...

journal_title：Acta tropica

authors： Woolhouse ME

更新日期：1991-09-01 00:00:00

abstract：:The expression of variable antigen types (VATs) was determined among dividing populations of T. congolense growing in vivo in rabbit chancres and in vitro on bovine aorta endothelial cell monolayers. Experiments were performed in which a single metacyclic VAT (M-VAT) was deleted from a cultured metacyclic population b...

journal_title：Acta tropica

authors： Sutherland DV,Ross CA,Luckins AG

更新日期：1991-08-01 00:00:00

abstract：:Adults of three ampullariid species were examined for their ability to affect the population growth of Biomphalaria glabrata (M line strain) under laboratory conditions in which food (lettuce) was supplied ad libitum over an eleven week interval. Lanistes carinatus and Pila ovata were obtained from Kenya, and Marisa c...

journal_title：Acta tropica

authors： Stryker GA,Koech DK,Loker ES

更新日期：1991-06-01 00:00:00

abstract：:Erythrocyte survival was studied in 17 Thai patients (10 males, 7 females; aged 13-57 years) with severe falciparum malaria. To ensure radioisotopic labelling of cells before bone marrow recovery and survival analysis under near-steady state conditions, 51Cr labelling of autologous erythrocytes was performed at the ti...

journal_title：Acta tropica

authors： Looareesuwan S,Davis TM,Pukrittayakamee S,Supanaranond W,Desakorn V,Silamut K,Krishna S,Boonamrung S,White NJ

更新日期：1991-02-01 00:00:00

abstract：:We used previously immunized (partially resistant) and naive (highly susceptible) BALB/c mice infected with Leishmania amazonensis for evaluating the role of granulocytes in the course of murine leishmaniasis. The animals were examined at different times post-infection and granulocytes counted in lesion tissues examin...

journal_title：Acta tropica

authors： Pompeu ML,Freitas LA,Santos ML,Khouri M,Barral-Netto M

更新日期：1991-01-01 00:00:00

abstract：:Indirect fluorescent antibody (IFA) tests and enzyme-linked immunosorbent assays (ELISA) were used to measure antibodies to Plasmodium falciparum in an indigenous population in an area of Malaysia with high malaria prevalence. The results of three surveys were analyzed to examine the relation of these serologic measur...

journal_title：Acta tropica

authors： Archibald CP,Mak JW,Mathias RG,Selvajothi S

更新日期：1990-12-01 00:00:00

abstract：:We examined the malaria situation among 489 children under 5 years of age in the rural villages of Aboh Mbaise, Nigeria, using a combination of a standard questionnaire technique and laboratory diagnosis to confirm clinical observations. The results show a high prevalence rate of 52.8% for Plasmodium falciparum in thi...

journal_title：Acta tropica

authors： Ejezie GC,Ezedinachi EN,Usanga EA,Gemade EI,Ikpatt NW,Alaribe AA

更新日期：1990-10-01 00:00:00

abstract：:The nematode cuticle is an extracellular structure composed mainly of collagens, with an insoluble epicuticle on the surface. The extracted collagens from adult Ascaris suum can be separated by SDS-PAGE into three major groups of polypeptides with apparent molecular masses of 34, 60-70 and 120-140 kDa. Densitometric e...

journal_title：Acta tropica

authors： Betschart B,Wyss K

更新日期：1990-07-01 00:00:00

abstract：:The insect molting hormone and related compounds (ecdysteroids) have been found in patients infected with helminths. To investigate this phenomenon, we quantified and analyzed the urinary ecdysteroids in Malian subjects suffering from various helminthiases, as well as in Europeans. Very high titers (up to 100 nM) were...

journal_title：Acta tropica

authors： Baswaïd S,Gharib B,Doumbo O,Quilici M,de Reggi M

更新日期：1990-05-01 00:00:00

abstract：:Homidium bromide was used in a strategic chemoprophylactic regime to control trypanosomiasis in Boran cattle in Kenya. Trypanosome infection rates in cattle receiving homidium bromide prophylaxis were compared with those in control cattle which received no prophylaxis but were treated with diminazene aceturate when in...

journal_title：Acta tropica

authors： Dolan RB,Okech G,Alushula H,Mutugi M,Stevenson P,Sayer PD,Njogu AR

更新日期：1990-03-01 00:00:00

abstract：:The administration of flurbiprofen, a potent non-steroidal anti-inflammatory drug (NSAID), to goats infected with trypanosomes resulted in high elevated parasitaemia and suppression of fever. In contrast to goats, rats infected with trypanosomes do not show febrile reactions. Therefore, the role of body temperature wa...

journal_title：Acta tropica

authors： Zwart D,Brun R,Dwinger RH,van Miert AS,Franssen FF,Nieuwenhuijs J,Kooy RF

更新日期：1990-02-01 00:00:00